COVID-19 and Traffic Accidents: Is a COVID-19 Personality Disorder Caused by Viral Damage to the Prefrontal Cortex?

View OpEd: https://www.infectioncontroltoday.com/view/covid-19-traffic-accidents-covid-19-personality-disorder-caused-viral-damage-prefrontal-cortex-

References:

1. Major Cities Chiefs Association. Violent Crime Survey - National Totals. Jan. 1 to June 30, 2022. https://majorcitieschiefs.com/wp-content/uploads/2022/08/MCCA-Violent-Crime-Report-2022-and-2021-Midyear.pdf

2. Schemmel A. Study mocked for linking COVID vaccine hesitancy to traffic accidents. Fox Illinois. Dec. 14, 2022. https://foxillinois.com/news/nation-world/study-mocked-for-linking-covid-vaccine-hesitancy-to-traffic-accidents-the-american-journal-of-medicine

3. Redelmeier DA, Wang J, Thiruchelvam D. The American Journal of Medicine. Dec. 2, 2022. https://foxillinois.com/news/nation-world/study-mocked-for-linking-covid-vaccine-hesitancy-to-traffic-accidents-the-american-journal-of-medicine

4. Sutin AR, Stephan Y, Luchetti M, et al. Differential personality change earlier and later in the coronavirus pandemic in a longitudinal sample of adults in the United States. PLOS ONE. Sept. 28, 2022. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0274542

5. Milojev P, Osborne D, Sibley CG, et al. Personality Resilience Following a Natural Disaster. Social Psychological and Personality Science. Apr. 11, 2014. https://doi.org/10.1177/1948550614528545

6. Damian RI, Serrano S, Hill PL. Hurricane exposure and personality development. Personality. Feb. 7, 2020. https://onlinelibrary.wiley.com/doi/10.1111/jopy.12542

7. Barrash J, Bruss J, Anderson SW, et al. Lesions in different prefrontal sectors are associated with different types of acquired personality disturbances. Cortex. Feb. 2022. https://www.sciencedirect.com/science/article/abs/pii/S0010945221003890

8. Miller EK. The prefrontal cortex and cognitive control. Nat. Rev. Neurosci. 2000 Oct;1(1):59-65. doi: 10.1038/35036228. https://pubmed.ncbi.nlm.nih.gov/11252769/

9. Blair RJR. The roles of orbital frontal cortex in the modulation of antisocial behavior. Brain Cogn
. 2004 Jun;55(1):198-208. doi: 10.1016/S0278-2626(03)00276-8. https://pubmed.ncbi.nlm.nih.gov/15134853/

10. Stein SR, Ramelli SC, Grazoli A, et al. SARS-CoV-2 infection and persistence in the human body and brain at autopsy. Nature. Dec. 14, 2022. https://www.nature.com/articles/s41586-022-05542-y

11. Douaud G, Lee S, Alfaro-Almagro F, et al. SARS-CoV-2 is associated with changes in brain structure in UK Biobank. Nature. Mar. 7, 2022. https://www.nature.com/articles/s41586-022-04569-5

12. Najafloo R, Majidi J, Asghari A, et al. Mechanism of Anosmia Caused by Symptoms of COVID-19 and Emerging Treatments. ACS Chem Neurosci. 2021 Oct 20; 12(20): 3795–3805. doi: 10.1021/acschemneuro.1c00477 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507153/

13. Crunfli F, Carregari VC, Veras FP, et al. Morphological, cellular, and molecular basis of brain infection in COVID-19 patients. Proceedings of the National Academy of Sciences. Aug. 11, 2022. oi: 10.1073/pnas.2200960119
https://doi.org/10.1073/pnas.2200960119

14. Toledo K. Study reveals main target of SARS-CoV-2 in brain and describes effects of virus on nervous system. Medical Xpress. Oct. 1, 2022. https://medicalxpress.com/news/2022-09-reveals-main-sars-cov-brain-effects.html

15. Hampshire A, Chatfield DA, MPhil AM, et al. Multivariate profile and acute-phase correlates of cognitive deficits in a COVID-19 hospitalised cohort. eClinicalMedicine. May 1, 2022. https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(22)00147-X/fulltext

16. Bowe, B., Xie, Y. & Al-Aly, Z. Acute and postacute sequelae associated with SARS-CoV-2 reinfection. Nat Med 28, 2398–2405 (2022). https://doi.org/10.1038/s41591-022-02051-3 https://www.nature.com/articles/s41591-022-02051-3#citeas

17. Johnson A. Can politics kill you? Research says the answer increasingly is yes. The Washington Post. Dec. 16, 2022. https://www.washingtonpost.com/health/2022/12/16/politics-health-relationship/

18. Krieger N, Testa C, DChen JT, et al. Relationship of political ideology of US federal and state elected officials and key COVID pandemic outcomes following vaccine rollout to adults: April 2021–March 2022. The Lancet Regional Health - Americas. Dec. 2022. https://doi.org/10.1016/j.lana.2022.100384

19. Sehgal NJ, Yue D, Pope E, et al. The Association Between COVID-19 Mortality And The County-Level Partisan Divide In The United States. Health Affairs. Jun. 2022. https://doi.org/10.1377/hlthaff.2022.00085

20. Wallace J, Goldsmith-Pinkham P, Schwartz PL. Excess Death Rates for Republicans and Democrats During the COVID-19 Pandemic. National Bureau of Economic Research. Sept. 2022. doi: 10.3386/w30512 https://www.nber.org/papers/w30512

21. Beauchamp Z. The bizarre far-right coup attempt in Germany, explained by an expert. Vox. Dec. 9, 2022. https://www.vox.com/2022/12/9/23500307/germany-coup-prince-heinrich-qanon

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